Does Using CoQ10 for Fatigue in MS REALLY Work?

Did someone suggest to you to take CoQ10 for fatigue? I'm not surprised.

CoQ10 (known as coenzyme Q10) has gotten quite a bit of attention lately as one of the definitive heart health all-natural supplement for people with heart disease. Some health experts claim that it is the "ultimate" energy production supplement.

Here's why. It is established that your cells need CoQ10 to generate energy. So it is reasonable, some experts suggest, that low blood levels of this essential enzyme could compromise this process and that this could lead to fatigue.

In the previous research studies, it has been suggested and demonstrated in research papers that depression is linked with low levels of CoQ10.

Indeed, patients suffering from Multiple Sclerosis (MS) patients commonly exhibit symptoms of fatigue and depression. Because of this, some researchers have proposed that CoQ10 might work for fatigue.

In my previous review on using CoQ10 for treating depression, it was shown that CoQ10 levels were very low in those individuals suffering from clinical depression.

If this is true, then taking a simple and safe natural supplement like CoQ10 might be one of the possible solutions for improving the quality of life.

Let's just look at one research study to find out if it actually works...

Research Study on the Benefits of Using CoQ10 for Fatigue in MS Patients

Multiple Sclerosis (MS) is a nervous system disorder that involves inflammation and destruction of the myelin, the insulating tissue for nerve cells.

If inflammation is involved, then CoQ10, being a potent antioxidant, may prove to be potentially helpful in reducing the damaging effects of the inflammation.

That's what this group of researchers wanted to uncover. Could giving MS patients help to reduce their symptoms of fatigue and depression?

The research team used a randomized placebo-controlled, double-blinded protocol over a 12 weeks period using a dosage of 500 mg of coenzyme Q10.

To judge the level of fatigue, the standardized Fatigue Severity Scale (FSS) was used. As for the severity of depression, they used the standardized Beck Depression Inventory (BDI) scale.

Over the 12 weeks of treatment, those individuals taking the CoQ10 reported significant decreases in both fatigue and depression symptoms compared to the group taking the look-a-like placebo "sugar" pill.

And because, the study involved a placebo group and randomization of the volunteers, we can be somewhat certain that the reported benefits were real and not because of the psychology of being told that what you are taking will help.

This is very good news indeed for those individuals suffering from MS as we have evidence that taking CoQ10 for reduces fatigue symptoms actually works.

Here's the reference to this study.

coq10 fatigue reference paper 1


What Dose Should I Start With?

In this study, the CoQ10 dose of 500 mg daily was used. It within the recommended range of 100 mg to 1,200 mg daily used in other research studies.

It is not known if a lower dose would work because the researchers started at 500 mg daily.

What I could suggest is to start with 100 mg or 200 mg daily and slowly increase to the 500 mg daily dose over several weeks. This is a logical approach.

What about taking higher than 500 mg daily? Perhaps. However, it would be a good idea to discuss this with your doctor first before taking a higher dose.

Bottom Line

Thinking of taking coenzyme Q10 to reduce fatigue?

It seem to be worth trying out.

This well-designed research study seemed to show that taking a CoQ10 supplement helps to cut down on the fatigue and depression experienced by many patients suffering from MS.

The simple conclusion from the research team is that they recommend it.

CoQ10 is low-cost, safe to use and is a naturally produced by the body. Additionally, it doesn't require a prescription from your doctor.

Fortunately, there are few reported side effects from taking a CoQ10 supplement.

In individuals suffering from MS, any remedy that works to improve the quality of their life is welcomed.