CoQ10 For Heart Failure - Does It Work?

It is scientifically established that CoQ10 improves heart function in individuals suffering from congestive heart failure (CHF).

Indeed most of the research studies conducted on coenzyme Q10 focus on its ability enhance the performance of a failing heart.

Let's look at several clinical studies to find out exactly how effective CoQ10 is in the treatment of heart failure...

Research Studies on CoQ10 for Heart Failure

There are over 30 published clinical studies related to the use and the effects of CoQ10 on heart failure patients. Most of them reported significant improvements in heart muscle function by taking a coenzyme Q10 supplement.

Those studies that also tracked the level of side effects of CoQ10 reported very few. CoQ10, even in very high doses, was very well tolerated.

We will summarize the results of four clinical trials and the conclusions from these research studies.

Study #1

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In this 12 weeks study involving 53 volunteers, combining CoQ10 with pycnogenol significantly improved the heart's ability to pump blood.

Moreover, they were able to walk over 3 times as far on a treadmill before becoming fatigued compared to those who were on the placebo (sugar pill).

Study #2

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It is a known that prescription "statins" cholesterol medications (such a Zocor, Lipitor, Mevacor and Crestor) lower CoQ10 levels significantly.

The important conclusion from this study was that, while Crestor lowered the cholesterol levels, it also lowered the CoQ10 levels.

Low CoQ10 levels increase the risk of oxidation of the fats that deposit on the inside of blood vessels. This leads to atherosclerosis or hardening of the arteries.

Note: If you are taking any type of "statins" type cholesterol lowering medication, it is essential to take a CoQ10 supplement. This is an established benefit as shown in many scientific studies.

Study #3

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Patients suffering from congestive heart failure have lower levels of CoQ10 than in the general population. This study involved seven subjects with advanced congestive heart failure.

The researchers provided CoQ10 supplement ranging in dose from 450 to 900 mg per day and tracked the blood levels of CoQ10 as well the heart's left ventricular function. (The left ventricle is the chamber of the heart responsible for pumping blood to the entire body).

The results are that the blood levels of CoQ10 improved dramatically with a matching improvement in the heart's ability to pump blood.

Clearly, in these individuals, a high dose of CoQ10 offered significant benefits in improving heart function.

Study #4

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Giving subjects 100 mg three times daily of CoQ10 supplements resulted in significant improvements in the strength of the heart muscle contraction when combined with exercise training.

This was the conclusion from the researchers in this double-blinded placebo-controlled cross-over study involving 23 patients suffering from chronic heart failure.

The researchers noted that with a dose of 100 mg of CoQ10 three times daily, the CoQ10 plasma levels in these volunteers increased three fold.

CoQ10 for heart failure - Dose used in the studies

The clinical studies used doses all the way up to 900 mg per day of CoQ10 for advanced congestive heart failure subjects.

Since heart failure is a serious health condition, we would suspect that high doses of CoQ10 would be needed.

Patients with heart failure cannot self-medicate and as such, even the use of CoQ10 should be supervised by a competent health care professional. This is especially true for dosages higher than 200 mg per day.

Bottom line

Does it help to take CoQ10 for heart failure?

Yes it does. Extensive clinical studies proved the benefits of taking CoQ10 for heart failure.

The recommended dosage would depend on the severity of the heart failure.

We would suggest a minimum of 200 mg daily as a starting dose.

Higher dose may be required and supervision by a doctor is recommended.

See Health Benefit of Coenzyme Q10 to discover all the other benefits of this natural substance.

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References for CoQ10 for Heart Failure

Revised: May 11, 2012