evidence shows that this supplement is very helpful in treating
arthritis pain. It also seems to slow down the degeneration of the
Obviously pain free movement is what you
are trying to achieve. Freedom from pain should occur once the joint is
sufficiently repaired. This might be the reason why some research shows
GS to be not as effective as would be expected. Everyone have
levels of joint damage and tolerance to pain.
In addition, sulfate is
required for the regeneration of the cartilage. It has been suggested
by researchers that GS would be more effective than glucosamine
hydrochloride. Knowing this, we will suggest GS (and not the
hydrochloride form) combination products that also contain chondroitin and MSM.
We believe there
will be no difference in the capsule, powder or liquid formulation;
they would be equally effective if they contained identical ingredients.
you suffer from osteoarthritis, we recommend a dosage of 500 mg taken
three times daily (1,500 mg daily dose) along with chondroitin 200 to 400 mg
three times daily. It works and it is supported by scientific research.
studies show that GS at dosages of 2 grams daily helps with reducing
A well-designed three year study showed reduction in pain
and no further joint space damage for the group taking 1500 mg of GS
daily compared to placebo (sugar pill).
benefits of GS for treating osteoarthritis varies. Overall, there are
many positive results of using GS (alone or in combination with
chondroitin or MSM). There are also reports that show glucosamine is no
better than placebo.
One research study
showed that GS can cross the skin to work in the joint space. However,
buy GS cream that also have other useful ingredients such menthol,
camphor, capsaicin, MSM and/or Celadrin. This will increase the
pain-relieving benefits of the cream.
research studies suggest GS can be used to treat people with back
pains. More research will be required to further prove this. We expect
similar benefits so it is definitely worth taking for treating back
is either made synthetically or from marine exoskeletons (shrimp,
lobster and crabs). The form GS is made synthetically. GS is needed by
your body to make products (mucopolysaccharides) for forming and
regenerating tendons, cartilage, ligaments and synovial fluid (fluids
found in the joints). As we age, we loose some of it in our body,
causing the cartilage to thin.
quick review of literatures shows that more studies are done with GS
than the hydrochloride form. Studies done with GS give better results
than with the hydrochloride form. Thus we recommend that it is best to
use GS rather than the hydrochloride form.
Most studies measure pain
relief when doing research on GS. The perception of pain is very
subjective and varies a lot from individual to individual. There are
very little studies that looked at the actual joint by x-ray or
arthroscopy. One study showed that GS made a modest improvement in the
quality of the cartilage of the knee joint.
More research studies are available for GS than
with the hydrochloride form. As sulfate is also required for making and
repairing cartilage, researchers believe that using GS rather
hydrochloride form would be a better choice.
My dog (or cat) suffers from arthritis pain? Can
they take it?
GS and combination
supplements have been used safely in dogs by vets to treat
arthritis. It is definitely worthwhile to give it a try for your
beloved pet. The good news is that there are no "placebo" problems when
you give it to your canine or feline! They have no clue as to what you
are giving to them. If it works, you'll absolutely know that it is not
because it's in their head!
There are positive results in studies of using supplements
in animals such as dogs and cats.
can buy the formulation sold in pharmacies or health food stores
designed for human use (perhaps in the liquid formulation).
will save you money as the pet specific formulation do cost
How fast does it work?
people is under the false impression that glucosamine sulfate (GS) is
designed to help with arthritis pain. It is not a pain relief
medication in itself; it is designed to provide more of the substance
needed to allow the cartilage to regenerate and repair itself.
could take many months, and possibly upwards of a year before you get
pain relief from taking GS. However, some people can get relief from
pain in as short as a week. It all depends on the severity
So does it cure arthritis?
all depends on the health status of your joints. GS may not be able to
repair severely damaged arthritic joints. However, it is shown that GS
can prevent further joint damage and at the least, slow down the
progression of this debilitating disease.
I hear that it's better to combine this with
chondroitin. Is this true?
is also needed and studies show that you get better pain relief than
just taking glucosamine by itself. This combination is the
we suggest you take. You may also want to consider taking MSM
as well. These three
combinations are often found in products marketed to treat arthritis
Suggested Benefits and
Transdermally (through the skin)
- osteoarthritis of the knee
- back pain
- joint pain
Effects, Toxicity and Warnings
might cause stomach related side effects such as bloating and cramps.
Other side effects reported include constipation, diarrhea, drowsiness,
nausea, headaches and skin rash.
Some studies suggest that GS might
affect blood sugar levels in people with diabetes but additional
studies done showed no such effects. This is not a significant risk if
your diabetes condition is under control. If you have diabetes, monitor
your blood sugar levels closely when you start glucosamine.
A review of current research shows that GS does not affect the
cholesterol levels or blood pressure.
Safety - Many studies have
that oral GS is safe to use in research studies lasting up to 3 years.
Topically applied GS cream are safe. Some combination of glucosamine
creams might contain other ingredients (such as capsaicin) that might
cause skin irritation and a burning sensation.
Warfarin - Caution
can increase the blood-thinning effect of warfarin or ASA (Aspirin).
Monitor closely when you start or stop taking GS while on warfarin.
Consult a healthcare profession and report any usual bleeding.
Diabetes - Potential concern
sugar levels if you are starting on GS.
& How to Take It
typical dosage of GS is 500 mg taken three times daily.
GS can also be
taken as 750mg twice daily.
Often, GS is combined with other products
such as chondroitin, MSM (methylsulfonylmethane), bromelain, boswellia
and/or devil's claw.
Various GS cream formulations also contain
menthol, camphor, capsaicin, chondroitin
Celadrin. They are
all applied by rubbing onto the affected joints two to four times daily.
GS can be found in powder, liquid, tablet and capsule formulation
either alone or with other supplements.
Osteoarthritis - Natural Remedies
Recommended Diet for Arthritis Pain
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